王冬梅

　　 　　

[基本信息]

王冬梅，女，博士，教授，博士研究生导师。陕西省经济植物资源开发利用重点实验室主任、中国林学会经济林协会加工利用分会常务理事、陕西省天然药物学会理事、西北农林科技大学“青年学术骨干”、美国康奈尔大学访问学者。现任林学院林产化工系主任。

[研究方向]

1. 特色林源活性物质分离、结构鉴定及其应用。

2. 活性物质胞内高效合成及其代谢调控。

3. 林源生物活性复合高分子材料制备及其应用。

[学术成果]

（一）近年主持的科研项目：

1. 国家自然基金面上项目，基于1H-NMR代谢组学和转录组学的花椒种质资源研究，31872706，2019-2022年，在研，主持

2. 国家十三五重点研发项目子课题，花椒色素形成及其代谢调控网络解析，2019YFD1000603-5，2019-2022，在研，主持

3. 国家十三五重点研发项目子课题，橡胶用和药用杜仲定向培育与高效利用关键技术研究，2017YFD0600702，2017-2020，在研，主持

4. 陕西省重点研发计划，花椒叶活性组分高效制备关键技术及其产品开发，2017NY-030，2017-2019，结题，主持

5.  国家林业公益性行业科研专项，林源食用叶类深加工与产品质量控制技术研究，201304811，2013-2016，结题，子课题主持

6. 国家林业公益性行业科研专项，200904004，秦岭林药资源保护及开发利用技术研究，2009-2013，结题，子课题主持

7. 中央高校基本科研业务费重点项目，金露梅与银杏的抗氧化协同效应及其机制研究，ZD2013010，2013-2015，结题，主持。

（二）发表论文：

近年发表的相关研究论文（第一作者或通讯作者）：

1. Wu Zhaochen, Wang Wei, Sun Leiwen, Wei Anzhi, Wang Dongmei*. Accumulation and biosynthesis of hydroxyl-α-sanshool in varieties of  Zanthoxylum bungeanum Maxim.  by HPLC-fingerprint and transcriptome analyses. Industrial Crops and Products, 2020，145:111998

2. Sun Leiwen, Yu Danmeng, Wu Zhaochen, Wang Cheng, Yu Li, Wei Anzhi, Wang Dongmei*. Comparative transcriptome analysis and expression of genes reveal the biosynthesis and accumulation patterns of key flavonoids in different varieties of  Zanthoxylum bungeanum  Leaves. Journal of Agricultural and Food Chemistry, 2019, 67(48): 13258-13268.

3. Chen Xiaoqi，Wang Wei，Wang Cheng, Liu Zijia, Sun Qi, Wang Dongmei*. Quality evaluation and chemometric discrimination of  Zanthoxylum bungeanum Maxim  leaves based on flavonoids profiles, bioactivity and HPLC-fingerprint in a common garden experiment. Industrial Crops and Products, 2019, 134: 225-233.

4. Liu Zehua, Kuang Shun, Qing Mingliang, Wang Dongmei*, Li Dengwu. Metabolite profiles of essential oils and SSR molecular markers in  Juniperus rigida  Sieb. et Zucc. from different regions: A potential source of raw materials for the  perfume and healthy products. Industrial Crops and Products, 2019, 133: 424-434.

5. Zhou Dan, Liu Zehua, Wang Dongmei*, Li Dengwu, Yang Lina, Wang Wei. Chemical composition, antibacterial activityand related mechanism of valonia and shell from  Quercus variabilis  Blume (Fagaceae) against  Salmonella paratyphia  and  Staphylococcus aureus , BMC Complementary and Alternative Medicine, 2019, 19:271.

6. Zhang Yawei, Yang Lina, Wang Dongmei*, Li Dengwu. Structure elucidation and properties of different lignins isolated from acorn shell of  Quercus variabilis  Bl，Journal of Biological Macromolecules, 2018, 107: 1193-1202.

7. Wu Zhaochen, Wang Wei, He Fengyuan, Li Dengwu, Wang Dongmei*. Simultaneous enrichment and separation of four flavonoids from  Zanthoxylum bungeanum  leaves by ultrasound-assisted extraction and macroporous resins with evaluation of antioxidant activities, Journal of food science, 2018, 83(8): 2109-2118.

8. Wu Dong, Yu Danmeng, Zhang Yujia, Dong Juane, Li Dengwu, Wang Dongmei*. Metabolite profiles, bioactivity, and HPLC fingerprint of different varieties of  Eucommia ulmoides  Oliv.: towards the utilization of medicinal and commercial Chinese endemic tree. Molecules, 2018, 23(8): 1898.  

9. Zehua Liu, Dongmei Wang*, Dengwu Li*，Shuai Zhang. Quality evaluation of  Juniperus rigida Sieb. et Zucc. based on phenolic profiles, bioactivity, and HPLC fingerprint combined with chemometrics.  Frontiers in Pharmacology , 2017,8, 198.

10. Lina Yang, Dongmei Wang*, Dan Zhou, Yawei Zhang, Tingting Yang. Isolation and further structural characterization of lignins from the valonea of  Quercus variabilis  .   International Journal of Biological Macromolecules , 2017, 97, 164-172.

11. Lina Yang, Dongmei Wang*, Dan Zhou, Yawei Zhang. Effect of different isolation methods on structure and properties oflignin from valonea of  Quercus variabilis .  International Journal of Biological Macromolecules , 2016, 85, 417-424.

12. Dan Zhou, Dongmei Wang *, Lina Yang, Zehua Liu, Yawei Zhang. A modified and improved assay based on microbial test system (MTS) to evaluate antioxidant activity.  Food analytical method . 2016, 9(4): 895-904.

13. Zehua Liu, Dengwu Li, Dongmei Wang*, Ziwen Luo. Synergistic effects of  Potentilla fruticosa  L. leaves combined with green tea polyphenols in a variety of oxidation systems.  Journal of Food Science , 2016, C1091-1101.

14. Zehua Liu, Dongmei Wang*, Sufang Fan, Dengwu Li*, Ziwen Luo, Synergistic effects and related bioactive mechanism of  Potentilla fruticosa  L. leaves combined with  Ginkgo biloba  extracts studied with microbial test system (MTS), BMC Complementary and Alternative Medicine, 2016, 16:495

15. Fengyuan He, Dengwu Li, Dongmei Wang*, Ming Deng. Extraction and purification of quercitrin, hyperoside, rutin and afzelin from  Zanthoxylum bungeanum  Maxim leaves using an aqueous two-phase system. Journal of Food Science, 2016, C1593-1602.

16. Yawei zhang, Fengyuan He, Dengwu Li, Dongmei Wang*. Effects of high temperature steam treatment on microbial and phytochemical contents, antioxidant activities, stability and shelf life of oral liquid prepared from the leaves of  Zanthoxylum bungeanum  Maxim.  Journal of Food Processing and Preservation , 2016, DOI 10.1111/jfpp.13180.

17. Ziwen Luo, Shanshan Wang, Dongmei Wang*. Phenolic profiles and antioxidant capacities of crude extracts and subsequent fractions from  Potentilla fruticosa  L. leaves. Natural Product Research, 2016, 1890-1895.

18. Wenjun Pu, Dongmei Wang*, Dan Zhou. Structural characterization and evaluation of the antioxidant activity of phenolic compounds from  Astragalus taipaishanensis  and their structure-activity relationship.  S  cientific reports , 2015:13914.

19. Shanshan Wang, Dongmei Wang*, Zehua Liu. Synergistic, additive and antagonistic effects of  Potentilla fruticosa  combined with EGb761 on antioxidant capacities and the possible mechanism.  Industrial Crops and Products,  2015, 67, 227-238.

20. Dongmei Wang, Chengchen Zhang, Qiang Zhang, Nusrat Shafiq, Gennaro Pescitelli, Dengwu Li, Jinming Gao .Wightianines A−E, dihydro-β- agarofuran sesquiterpenes from  Parnassia wightiana , and their antifungal and insecticidal activities.  Journal of Agriculture and Food Chemistry , 2014, 62, 6669− 6676.

21. Yujuan Zhang, Dongmei Wang*, Lina Yang, Dan Zhou, Jingfang Zhang. Purification and characterization of flavonoids from the leaves of  Zanthoxylum bungeanum  and correlation between their structure and antioxidant activity.  Plos one , 2014, 9(8）: dio:10.1371/journal.pone. 0105725.

22. Dongmei Wang, Fengyuan He, Zhenjiang Lv, Dengwu Li. Phytochemical composition, antioxidant activity and HPLC fingerprinting profiles of three  Pyrola species from different regions.  Plos one , 2014, 9(5): doi:10.1371/journal.pone. 0096329.

23. Yujuan Zhang, Ziwen Luo, Dongmei wang*. Efficient quantification of the phenolic profiles of  Zanthoxylum bungeanum  leaves and correlation between chromatographic fingerprint and antioxidant activity.  Natural Product Research , 2015, 2015, 29(21): 2024-2029.

24. Yujuan Zhang, Ziwen Luo, Dongmei Wang*, Fengyuan He, Dengwu Li. Phytochemical profiles and antioxidant and antimicrobial activities of the leaves of  Zanthoxylum bungeanum .  Scientific World Journal , 2014, 181072. doi. 10.1155/2014/181072.

25. Jiangjiang Tang,  Feiyu Zhang, Dongmei Wang，Junmian Tian, Shuai Dong,  Jinming Gao. Semisynthesis and antifeedant activity of new derivatives of a dihydro-b-agarofuran from  Parnassia wightiana .  International Journal of Molecular Sciences , 2013, 14, 19484−19493.

26. Shanshan Wang, Dongmei Wang*, Wenjun Pu, Dengwu Li. Phytochemical profiles, antioxidant and antimicrobial activities of three  Potentilla species .  BMC complementary and alternative medicine , 2013, 13: 321.

27. Dongmei Wang, Liang Zeng, Dengwu Li, Wenjun Pu. Antioxidant activity of different extracts and homoisoflavanones isolated from the  Polygonatum odoratum .  Natural product research , 2013, 27(2): 1111−1114.

28. Dongmei Wang, Yujuan Zhang, Shanshan Wang, Rui Zhou. Antioxidant and antifungal activities of extracts and fractions from  Anemone taipaiensis , China.  Allelopathy Journal , 2013, 32(1): 67−78.

29. Y.X. Kang, C.C. Zhang, Dongmei Wang*. Antifungal activities of  Potentilla fruticosa  on 12 fungi spp.  Allelopathy Journal , 2013, 31(2): 405−414.

30. Yuejin Zhang, Xuanming Zhang, Yan Ma, Jin Wang, Kang Yongxiang, Dongmei Wang*. Correlation analysis between the high-performance liquid chromatography （HPLC）fingerprint of antioxidants and flavonoids of  P  olygonatum odorantum.  Journal of medicinal plant research , 2013, 7(17), 1114-1120.

31. Dongmei wang ,Wenjun Pu, Yonghong Wang, Yujuan Zhang , Shanshan Wang . A new isorhamnetin glycoside and other phenolic compounds from  Callianthemum taipaicum .  Molecules , 2012, 17(4), 4595−4603.

32. Dongmei Wang, Dengwu Li, Wei Zhu, Pai Peng. A new C-methylated       homoisoflavanone and triterpenoid from the rhizomes of  Polygonatum odoratum .  Natural Product Research , 2009, 23(6), 580−589.

33. Dongmei wang , Dengwu Li, Wei Zhu, Jingfang Zhang, Pai Peng. Steriodal saponins from the rhizomes of  Polygonatum odoratum .  Natural Product Research , 2009, 23(10), 940−947.

34. Dongmei wang, Dengwu Li, Wei Zhu, Pai Peng. Chemical constituents with antisepsis activity from the rhizomes of  Polygonatum odoratum. Chemistry of Natural compounds , 2009, 45(6), 733−735.

（三）专利：

1. 王冬梅，浦文君，李登武，刘建军。苍耳七中2-酮型-β-二氢沉香呋喃倍半萜类化合物其制备方法及应用，2015，ZL2013 1 0023928.

2. 王冬梅，何枫媛，张京芳，李登武. 一种花椒叶口服液及其制备方法，201510027061.1.

3. 一种从杜仲叶中连续提取活性物质的方法（ZL01128743.8，2006）.

（四）参编、著书：

1. 参编，《植物化学》．北京：科学出版社，2012

2. 参著，《中国杜仲次生代谢物》．北京：科学出版社，2002

(五) 获奖情况：

1. 徐怀德，任亚梅，罗安伟，王冬梅等. 花椒深加工与综合利用研究. 杨凌示范区科学技术进步一等奖，2016

2. 获2009年、2018年度西北农林科技大学“优秀教师”称号。

[联系方式]

通讯地址：陕西杨凌邰城路3号 西北农林科技大学林学院   邮编：712100

Email: dmwli@163.com